Medical Mathematics

During the Renaissance, anatomy got great advance with the help of mathematics. After John Snow, mathematics especially statistics accerelated epidemiology and medicine. We are at the dawn of a new ara, that is, mathematician are trying to describe biochemical mechanisms of intra cellular and inter cellular cascades. They are still trial works, but improving day by day.

In these days Big Data Analysis (BDA) is one of the topic. Most expects it to reveal a lot of new facts. From statistical point of view, BDA has danger of false positive. If the sample size is 100 and specificity is 99%, then false positive is only one. If the sample reached one million, then false positive comes to 10,000. False positive grows according to the sample size. To reduce this problem, the best way is to make more strict population which is brougt by medical mathematics.